Serotonin Specific Re-uptake Inhibitors (SSRI drugs) are often prescribed for depression and anxiety. They are also known to increase the risk of homicide, suicide or self-harm. None of these outcomes have been associated with cannabis use.
These synthetic SSRI drugs are known to be toxic in high doses, and deaths have been recorded from overdose. Cannabis, on the other hand, is one of the least toxic medically active drugs known – there are no credible cases of death from cannabis overdose on record.
The efficacy of these SSRI drugs is now also in doubt, whereas there seems to be a strong consensus throughout history and all over the world that cannabis is a powerful and effective anti-depressant and relaxant.